Insights into the pathogenesis of eosinophilic esophagitis using mouse models
Download PDF Share Subscribe
logo
All Journals Login

Myeloid Cells
  1. Home
  2. Articles
  3. Article

Insights into the pathogenesis of eosinophilic esophagitis using mouse models

Anish Dsilva
1
,
Ariel Munitz
1,2,*
*Correspondence to: Ariel Munitz, Department of Clinical Microbiology and Immunology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Ramat Aviv 69978, Israel. E-mail: arielm@tauex.tau.ac.il
Myeloid Cells. 2026;1:202604. 10.70401/mc.2025.0003
Received: March 24, 2026Accepted: May 18, 2026Published: May 18, 2026
Tips Icon
This manuscript is made available in its unedited form to allow early access to the reported findings. Further editing will be completed before final publication. As such, the content may include errors, and standard legal disclaimers are applicable.

Abstract

Eosinophilic esophagitis (EoE) is a chronic, food antigen-driven, type 2 immune-mediated disease of the esophagus characterized by eosinophil-predominant mucosal inflammation, epithelial remodeling and subepithelial fibrosis. Although patient biopsies have established the EoE transcriptome and identified key cellular and molecular mediators, biopsy-based research is inherently correlative and cannot resolve causal disease mechanisms, temporal disease progression or the functional hierarchy of immune cell interactions. Thus, animal models are indispensable tools for addressing these limitations. In this Review, we examine the landscape of experimental EoE models. We assess the capacity of each model to recapitulate key disease features including lamina propria and intraepithelial eosinophilia, subepithelial fibrosis, basal cell hyperplasia, epithelial barrier dysfunction and angiogenesis. We further map these models to human EoE transcriptomic overlap and disease endotype relevance. Across this analysis, we highlight mechanistic insights that were obtained from these models including the eosinophil-independence of IL-13-driven esophageal remodeling, the respective roles of thymic stromal lymphopoietin and IL-33, the critical role of epithelial-expressed IL-13Rα1. We further highlight the profibrotic functions of amphiregulin-producing T helper 2 cells and CSF1-dependent macrophages. We discuss the anatomical, genetic and functional limitations of current models and outline directions for the next generation of EoE preclinical systems.

Keywords

EGIDs, eosinophilic esophagitis, allergy, IL-13, IL-13R1, TSLP, IL-33

References

  • 1. O’Shea KM, Aceves SS, Dellon ES, Gupta SK, Spergel JM, Furuta GT, et al. Pathophysiology of eosinophilic esophagitis. Gastroenterology. 2018;154(2):333-345.
    [DOI]
  • 2. Hoofien A, Dias JA, Malamisura M, Rea F, Chong S, Oudshoorn J, et al. Pediatric eosinophilic esophagitis: Results of the European retrospective pediatric eosinophilic esophagitis registry (RetroPEER). J Pediatr Gastroenterol Nutr. 2019;68(4):552-558.
    [DOI] [PubMed]
  • 3. Zifman E, Banai H, Shamir R, Ringel-Kulka T, Zevit N. Practice differences in the diagnosis and management of eosinophilic esophagitis among adult and pediatric gastroenterologists in Israel. J Pediatr Gastroenterol Nutr. 2018;67(1):34-39.
    [DOI]
  • 4. Hill DA, Spergel JM. The atopic March: Critical evidence and clinical relevance. Ann Allergy Asthma Immunol. 2018;120(2):131-137.
    [DOI] [PubMed] [PMC]
  • 5. Spergel J, Aceves SS. Allergic components of eosinophilic esophagitis. J Allergy Clin Immunol. 2018;142(1):1-8.
    [DOI]
  • 6. Corren J, Ziegler SF. TSLP: From allergy to cancer. Nat Immunol. 2019;20(12):1603-1609.
    [DOI] [PubMed]
  • 7. Comeau MR, Ziegler SF. The influence of TSLP on the allergic response. Mucosal Immunol. 2010;3(2):138-147.
    [DOI]
  • 8. Stanbery AG, Smita S, Von Moltke J, Wojno EDT, Ziegler SF. TSLP, IL-33, and IL-25: Not just for allergy and helminth infection. J Allergy Clin Immunol. 2022;150(6):1302-1313.
    [DOI]
  • 9. Martin NT, Martin MU. Interleukin 33 is a guardian of barriers and a local alarmin. Nat Immunol. 2016;17(2):122-131.
    [DOI]
  • 10. Han H, Roan F, Johnston LK, Smith DE, Bryce PJ, Ziegler SF. IL-33 promotes gastrointestinal allergy in a TSLP-independent manner. Mucosal Immunol. 2018;11(2):578.
    [DOI] [PubMed]
  • 11. Ziegler SF, Artis D. Sensing the outside world: TSLP regulates barrier immunity. Nat Immunol. 2010;11(4):289-293.
    [DOI] [PubMed] [PMC]
  • 12. Ziegler SF, Roan F, Bell BD, Stoklasek TA, Kitajima M, Han H. The biology of thymic stromal lymphopoietin (TSLP). Adv Pharmacol. 2013;66:129-155.
    [DOI]
  • 13. Rothenberg ME, Spergel JM, Sherrill JD, Annaiah K, Martin LJ, Cianferoni A, et al. Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet. 2010;42(4):289-291.
    [DOI]
  • 14. Kottyan LC, Rothenberg ME. Genetics of eosinophilic esophagitis. Mucosal Immunol. 2017;10(3):580-588.
    [DOI] [PubMed] [PMC]
  • 15. Davis BP, Stucke EM, Khorki ME, Litosh VA, Rymer JK, Rochman M, et al. Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment. JCI Insight. 2016;1(4):e86355.
    [DOI]
  • 16. Kottyan LC, Davis BP, Sherrill JD, Liu K, Rochman M, Kaufman K, et al. Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. Nat Genet. 2014;46(8):895-900.
    [DOI] [PubMed] [PMC]
  • 17. Sleiman PMA, Wang ML, Cianferoni A, Aceves S, Gonsalves N, Nadeau K, et al. GWAS identifies four novel eosinophilic esophagitis loci. Nat Commun. 2014;5:5593.
    [DOI]
  • 18. Martin LJ, He H, Collins MH, Abonia JP, Biagini Myers JM, Eby M, et al. Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci. J Allergy Clin Immunol. 2018;141(5):1690-1698.
    [DOI] [PubMed] [PMC]
  • 19. Sherrill JD, KC K, Wu D, Djukic Z, Caldwell JM, Stucke EM, et al. Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis. Mucosal Immunol. 2014;7(3):718-729.
    [DOI] [PubMed] [PMC]
  • 20. Dellon ES, Falk GW, Katzka DA, Lightdale J, Muir AB, Bredenoord AJ, et al. American Society for Gastrointestinal Endoscopy consensus recommendations on the endoscopic management of eosinophilic esophagitis-part 2: Disease assessment, monitoring, and pediatric considerations. Gastrointest Endosc. 2026;103(3):396-417.
    [DOI] [PubMed]
  • 21. Rochman M, Kellerman K, Jankowski MP, Rothenberg ME. The oesophagus as an immune organ. Nat Rev Gastroenterol Hepatol. 2025;22(9):657-667.
    [DOI] [PubMed] [PMC]
  • 22. Azouz NP, Ynga-Durand MA, Caldwell JM, Jain A, Rochman M, Fischesser DM, et al. The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses. Sci Transl Med. 2018;10(444):eaap9736.
    [DOI]
  • 23. Min S, Shoda T, Wen T, Rothenberg ME. Diagnostic merits of the Eosinophilic Esophagitis Diagnostic Panel from a single esophageal biopsy. J Allergy Clin Immunol. 2022;149(2):782-787.
    [DOI]
  • 24. Ben-Baruch Morgenstern N, Ballaban AY, Wen T, Shoda T, Caldwell JM, Kliewer K, et al. Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation, and activation that persists in remission. J Allergy Clin Immunol. 2022;149(6):2062-2077.
    [DOI] [PubMed] [PMC]
  • 25. Wen T, Aronow BJ, Rochman Y, Rochman M, KC K, Dexheimer PJ, et al. Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis. J Clin Invest. 2019;129(5):2014-2028.
    [DOI] [PubMed] [PMC]
  • 26. Ding J, Garber JJ, Uchida A, Lefkovith A, Carter GT, Vimalathas P, et al. An esophagus cell atlas reveals dynamic rewiring during active eosinophilic esophagitis and remission. Nat Commun. 2024;15:3344.
    [DOI]
  • 27. Li D, Wei Y, Wang J, Wang B. Animal models of eosinophilic esophagitis, review and perspectives. Anim Models Exp Med. 2024;7(2):127-135.
    [DOI]
  • 28. Avlas S, Shani G, Rhone N, Itan M, Dolitzky A, Hazut I, et al. Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis. Allergy. 2023;78(2):464-476.
    [DOI] [PubMed] [PMC]
  • 29. Wojno EDT, Noti M, Kim BS, Siracusa MC, Giacomin PR, Nair MG, et al. 282: TSLP-elicited basophil responses mediate the pathogenesis of eosinophilic esophagitis. Cytokine. 2013;63(3):310.
    [DOI]
  • 30. Lutzu N, Favale A, Demurtas M, Del Giacco S, Onali S, Fantini MC. Eosinophilic esophagitis in the “atopic March”: Dupilumab as an “umbrella” strategy for multiple coexisting atopic diseases. Front Med. 2025;11:1513417.
    [DOI]
  • 31. Venturelli N, Lexmond WS, Ohsaki A, Nurko S, Karasuyama H, Fiebiger E, et al. Allergic skin sensitization promotes eosinophilic esophagitis through the IL-33-basophil axis in mice. J Allergy Clin Immunol. 2016;138(5):1367-1380.
    [DOI] [PubMed]
  • 32. Davis BP. Pathophysiology of eosinophilic esophagitis. Clin Rev Allergy Immunol. 2018;55(1):19-42.
    [DOI] [PubMed]
  • 33. Visaggi P, Dellon ES. Epidemiology, natural history, and treatment of eosinophilic gastrointestinal diseases. Gastroenterology. 2026;170(3):476-494.
    [DOI]
  • 34. Kaneko T, Iwamura C, Kiuchi M, Kurosugi A, Onoue M, Matsumura T, et al. Amphiregulin-producing TH2 cells facilitate esophageal fibrosis of eosinophilic esophagitis. J Allergy Clin Immunol Glob. 2024;3(3):100287.
    [DOI]
  • 35. Benson TM, Markey GE, Hammer JA, Simerly L, Dzieciatkowska M, Jordan KR, et al. CSF1-dependent macrophage support matrisome and epithelial stress-induced keratin remodeling in Eosinophilic esophagitis. Mucosal Immunol. 2025;18(1):105-120.
    [DOI] [PubMed]
  • 36. Olson C, Alp J, Wongjarupong N, Sloan JA. Lessons learned: Real-world effectiveness of dupilumab in patients with eosinophilic esophagitis. Dis Esophagus. 2025;38(6):doaf123.
    [DOI]
  • 37. Marella S, Sharma A, Ganesan V, Ferrer-Torres D, Krempski JW, Idelman G, et al. IL-13-induced STAT3-dependent signaling networks regulate esophageal epithelial proliferation in eosinophilic esophagitis. J Allergy Clin Immunol. 2023;152(6):1550-1568.
    [DOI]
  • 38. Dellon ES, Charriez CM, Zhang S, Falk GW, Oliva S, Ma C, et al. Cendakimab in adults and adolescents with eosinophilic esophagitis. NEJM Evid. 2025;4(10):EVIDoa2500095.
    [DOI]
  • 39. Caldwell JM, Ballaban AY, Li J, Maddux R, Harris S, Dellon ES, et al. Cendakimab (anti-IL-13) administration improves esophageal gene expression in eosinophilic esophagitis. J Allergy Clin Immunol. 2026;157(1):118-130.
    [DOI] [PubMed]
  • 40. Dsilva A, Wagner A, Itan M, Rhone N, Avlas S, Gordon Y, et al. Distinct roles for thymic stromal lymphopoietin (TSLP) and IL-33 in experimental eosinophilic esophagitis. Allergy. 2025;80(11):3095-3107.
    [DOI]
  • 41. Masuda MY, Pyon GC, Luo H, LeSuer WE, Putikova A, Dao A, et al. Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-13. J Allergy Clin Immunol. 2024;153(5):1355-1368.
    [DOI]
  • 42. Pyon GC, Masuda MY, Putikova A, Luo H, Gibson JB, Dao AD, et al. Tissue-specific inducible IL-33 expression elicits features of eosinophilic esophagitis. J Allergy Clin Immunol. 2024;154(6):1545-1553.
    [DOI]
  • 43. Judd LM, Heine RG, Menheniott TR, Buzzelli J, O’Brien-Simpson N, Pavlic D, et al. Elevated IL-33 expression is associated with pediatric eosinophilic esophagitis, and exogenous IL-33 promotes eosinophilic esophagitis development in mice. Am J Physiol Gastrointest Liver Physiol. 2016;310(1):G13-G25.
    [DOI] [PubMed]
  • 44. Zuo L, Fulkerson PC, Finkelman FD, Mingler M, Fischetti CA, Blanchard C, et al. IL-13 induces esophageal remodeling and gene expression by an eosinophil-independent, IL-13Rα2-inhibited pathway. J Immunol. 2010;185(1):660-669.
    [DOI] [PubMed] [PMC]
  • 45. Ben Baruch-Morgenstern N, Mingler MK, Stucke E, Besse JA, Wen T, Reichman H, et al. Paired Ig-like receptor B inhibits IL-13-driven eosinophil accumulation and activation in the esophagus. J Immunol. 2016;197(3):707-714.
    [DOI] [PubMed] [PMC]
  • 46. Brusilovsky M, Rochman M, Shoda T, Kotliar M, Caldwell JM, Mack LE, et al. Vitamin D receptor and STAT6 interactome governs oesophageal epithelial barrier responses to IL-13 signalling. Gut. 2023;72(5):834-845.
    [DOI]
  • 47. Venkateshaiah SU, Shukla JS, Mishra A. IL-18 is induced in food allergic eosinophilic esophagitis (EoE) patients and its overexpression promotes disease pathogenesis in mice. J Allergy Clin Immunol. 2015;135(2):AB160.
    [DOI]
  • 48. Dutt P, Shukla JS, Ventateshaiah SU, Mariswamy SJ, Mattner J, Shukla A, et al. Allergen-induced interleukin-18 promotes experimental eosinophilic oesophagitis in mice. Immunol Cell Biol. 2015;93(10):914.
    [DOI] [PubMed]
  • 49. Akei HS, Mishra A, Blanchard C, Rothenberg ME. Epicutaneous antigen exposure primes for experimental eosinophilic esophagitis in mice. Gastroenterology. 2005;129(3):985-994.
    [DOI] [PubMed]
  • 50. Rubinstein E, Cho JY, Rosenthal P, Chao J, Miller M, Pham A, et al. Siglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2011;53(4):409-416.
    [DOI]
  • 51. Cho JY, Rosenthal P, Miller M, Pham A, Aceves S, Sakuda S, et al. Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis. Int Immunopharmacol. 2014;18(1):35-42.
    [DOI] [PubMed] [PMC]
  • 52. Ptaschinski C, Zhu D, Fonseca W, Lukacs NW. Stem cell factor inhibition reduces Th2 inflammation and cellular infiltration in a mouse model of eosinophilic esophagitis. Mucosal Immunol. 2023;16(5):727-739.
    [DOI] [PubMed] [PMC]
  • 53. Rajavelu P, Rayapudi M, Moffitt M, Mishra A, Mishra A. Significance of para-esophageal lymph nodes in food or aeroallergen-induced iNKT cell-mediated experimental eosinophilic esophagitis. Am J Physiol Gastrointest Liver Physiol. 2012;302(7):G645-G654.
    [DOI]
  • 54. Mishra A, Hogan SP, Brandt EB, Rothenberg ME. An etiological role for aeroallergens and eosinophils in experimental esophagitis. J Clin Invest. 2001;107(1):83-90.
    [DOI]
  • 55. Niranjan R, Mavi P, Rayapudi M, Dynda S, Mishra A. Pathogenic role of mast cells in experimental eosinophilic esophagitis. Am J Physiol Gastrointest Liver Physiol. 2013;304(12):G1087-G1094.
    [DOI] [PubMed] [PMC]
  • 56. Collison AM, Sokulsky LA, Sherrill JD, Nightingale S, Hatchwell L, Talley NJ, et al. TNF-related apoptosis-inducing ligand (TRAIL) regulates midline-1, thymic stromal lymphopoietin, inflammation, and remodeling in experimental eosinophilic esophagitis. J Allergy Clin Immunol. 2015;136(4):971-982.
    [DOI]
  • 57. Maskey A, Srivastava K, Soffer G, Dunkin D, Yuan Q, Li XM. Induction of severe eosinophilic esophagitis and multi-organ inflammation by airborne allergens is associated with IL-4/IL-13 and CCL11 but not IgE in genetic susceptible mice. J Inflamm Res. 2022;15:5527-5540.
    [DOI]
  • 58. Holvoet S, Doucet-Ladevèze R, Perrot M, Barretto C, Nutten S, Blanchard C. Beneficial effect of Lactococcus lactis NCC 2287 in a murine model of eosinophilic esophagitis. Allergy. 2016;71(12):1753-1761.
    [DOI]
  • 59. Lim M, Kim T, Kim H, Jang BG, Myung JK, Kim HY. Esophageal ILC2s mediate abnormal epithelial remodeling in eosinophilic esophagitis via Areg-EGFR signaling. Cell Mol Immunol. 2025;22(1):97-110.
    [DOI] [PubMed] [PMC]
  • 60. Dsilva A, Avlas S, Rhone N, Itan M, Munitz A. A mouse model for eosinophilic esophagitis (EoE). Curr Protoc. 2024;4(2):e993.
    [DOI] [PubMed] [PMC]
  • 61. Avlas S, Shani G, Rhone N, Itan M, Dolitzky A, Hazut I, et al. Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis. Allergy. 2023;78(2):464-476.
    [DOI]
  • 62. Siracusa MC, Saenz SA, Hill DA, Kim BS, Headley MB, Doering TA, et al. TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation. Nature. 2011;477(7363):229-233.
    [DOI] [PubMed] [PMC]
  • 63. Clevenger MH, Wei C, Karami AL, Tsikretsis LE, Carlson DA, Pandolfino JE, et al. Esophageal epithelial Ikkβ deletion promotes eosinophilic esophagitis in experimental allergy mouse model. J Allergy Clin Immunol. 2025;155(4):1276-1289.
    [DOI] [PubMed] [PMC]
  • 64. Masterson JC, McNamee EN, Hosford L, Capocelli KE, Ruybal J, Fillon SA, et al. Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis. Gut. 2014;63(1):43-53.
    [DOI] [PubMed] [PMC]
  • 65. Kellett SK, Crue T, Cruz SNA, Markey GE, Ryan S, Crowe L, et al. Resolution of epithelial dysfunction in eosinophilic esophagitis is mediated by an HIF-1α-CD73-adenosine signaling axis. J Allergy Clin Immunol. 2026;157(3):693-710.
    [DOI]
  • 66. Rothenberg ME, Dellon ES, Collins MH, Bredenoord AJ, Hirano I, Peterson KA, et al. Eosinophil depletion with benralizumab for eosinophilic esophagitis. N Engl J Med. 2024;390(24):2252-2263.
    [DOI]
  • 67. Häcker H, Chi L, Rehg JE, Redecke V. NIK prevents the development of hypereosinophilic syndrome-like disease in mice independent of IKKα activation. J Immunol. 2012;188(9):4602-4610.
    [DOI] [PubMed] [PMC]
  • 68. Eden K, Rothschild DE, McDaniel DK, Heid B, Allen IC. Noncanonical NF-κB signaling and the essential kinase NIK modulate crucial features associated with eosinophilic esophagitis pathogenesis. Dis Models Mech. 2017;10(12):1517-1527.
    [DOI]
  • 69. Laky K, Kinard JL, Li JM, Moore IN, Lack J, Fischer ER, et al. Epithelial-intrinsic defects in TGFβR signaling drive local allergic inflammation manifesting as eosinophilic esophagitis. Sci Immunol. 2023;8(79):eabp9940.
    [DOI]
  • 70. Shoda T, Wen T, Aceves SS, Abonia JP, Atkins D, Bonis PA, et al. Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: A cross-sectional study. Lancet Gastroenterol Hepatol. 2018;3(7):477-488.
    [DOI] [PubMed] [PMC]
  • 71. Doyle AD, Masuda MY, Pyon GC, Luo H, Putikova A, LeSuer WE, et al. Detergent exposure induces epithelial barrier dysfunction and eosinophilic inflammation in the esophagus. Allergy. 2023;78(1):192-201.
    [DOI] [PubMed] [PMC]
  • 72. Dellon ES, Rothenberg ME, Collins MH, Hirano I, Chehade M, Bredenoord AJ, et al. Dupilumab in adults and adolescents with eosinophilic esophagitis. N Engl J Med. 2022;387(25):2317-2330.
    [DOI]
  • 73. Chehade M, Dellon ES, Spergel JM, Collins MH, Rothenberg ME, Pesek RD, et al. Dupilumab for eosinophilic esophagitis in patients 1 to 11 years of age. N Engl J Med. 2024;390(24):2239-2251.
    [DOI]
  • 74. Kabir MF, Karami AL, Cruz-Acuña R, Klochkova A, Saxena R, Mu A, et al. Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium. Nat Commun. 2022;13(1):2167.
    [DOI] [PubMed] [PMC]
  • 75. Katori Y, Cho BH, Song CH, Fujimiya M, Murakami G, Kawase T. Smooth-to-striated muscle transition in human esophagus: An immunohistochemical study using fetal and adult materials. Ann Anat. 2010;192(1):33-41.
    [DOI]
  • 76. Alcolea MP. Oesophageal stem cells and cancer. Adv Exp Med Biol. 2017;1041:187-206.
    [DOI]
  • 77. Grommisch D, Eenjes E, Troost ML, Genander M. Epithelial architecture and signaling activity in the adult human esophagus. Front Cell Dev Biol. 2025;13:1632255.
    [DOI]
  • 78. Laserna-Mendieta EJ, FitzGerald JA, Arias-Gonzalez L, Ollala JM, Bernardo D, Claesson MJ, et al. Esophageal microbiome in active eosinophilic esophagitis and changes induced by different therapies. Sci Rep. 2021;11(1):7113.
    [DOI] [PubMed] [PMC]
  • 79. Osonoi K, Sawada A, Maekawa Y, Yamaguchi M, Yamada S, Matsuyama K, et al. Involvement of IL-13-induced dysregulation of BDNF-NTRK2 pathway in symptoms of eosinophilic esophagitis. Allergy. 2025;80(10):2894-2897.
    [DOI] [PubMed] [PMC]

© The Author(s) 2026. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Publisher’s Note

Science Exploration remains a neutral stance on jurisdictional claims in published maps and institutional affiliations. The views expressed in this article are solely those of the author(s) and do not reflect the opinions of the Editors or the publisher.

Share And Cite

×

Science Exploration Style
Dsilva A, Munitz A. Insights into the pathogenesis of eosinophilic esophagitis using mouse models. Myeloid Cells. 2026;1:202604. https://doi.org/10.70401/mc.2025.0003

Submit a Manuscript
Author Instructions
Cite this Article
Export Citation
Article Metrics
0
View
0
Download
Cited
Article Updates
Related Articles
Citation Icon Get citation

Myeloid Cells

mcjournal@sciexplor.com

Navigation

About the Journal
Editorial Process
Author Instructions
Editorial Board
Editorial Policies
Contact Us

Follow us